Chemotherapy drugs are used to treat cancer and other conditions in people because they target and kill rapidly dividing neoplastic (cancer) cells and other cells. They're primarily used as anti-cancer agents, but may also provide benefit for a variety of auto-immune disorders and for organ transplant recipients as immunosuppressive agents.
Yes, chocolate is toxic to dogs. While rarely fatal, chocolate ingestion often results in significant illness. Chocolate is toxic because it contains the alkaloid theobromine. Theobromine is similar to caffeine and is used medicinally as a diuretic, heart stimulant, blood vessel dilator, and a smooth muscle relaxant.
Congestive heart failure (CHF) is a term that refers to the heart's inability to pump adequate blood to the body. There are many causes of CHF in dogs. The two most common causes are mitral valve insufficiency (MVI), or a leaky mitral valve, the valve between the left atrium and the let ventricle and dilated cardiomyopathy (DCM).
The cornea is the clear, glistening membrane that makes up the surface of the eyeball. A penetration or erosion through a few layers of the outermost corneal epithelium is called a corneal erosion or corneal abrasion. A corneal ulcer is a deeper erosion through the entire epithelium down into the stroma.
The cornea is the transparent, shiny membrane that makes up the front of the eyeball. With a corneal ulcer, fluid is absorbed from the tears into the stroma, giving a cloudy appearance to the eye. The most common cause of a corneal ulcer is trauma. Less common causes of corneal ulcers include bacterial infections, viral infections, and other diseases.
When there is not enough oxygen being carried to the body by the red blood cells, the skin and mucous membranes can turn a bluish color. This is known as cyanosis.
Cystine bladder stones appear to be the result of a genetic abnormality that prevents a dog from reabsorbing cystine from the kidneys. While bladder stones in general are somewhat common in dogs, cystine bladder stones are rare. Your veterinarian may be able to palpate the stones or may need to perform imaging studies such as a bladder ultrasound or a contrast radiographic study. There are two primary treatment strategies for treating cystine bladder stones in dogs: urohydropropulsion or surgical removal. Dogs that have developed cystine bladder stones in the past will often be fed a therapeutic diet for life. Unfortunately, cystine stones have a high rate of recurrence, despite careful attention to diet and lifestyle.
Cystitis is a general term referring to inflammation in the urinary bladder. The term cystitis does not imply a specific underlying cause. In cats, diseases of the lower urinary tract (bladder and urethra) are often grouped under the term feline lower urinary tract disease (FLUTD). The initial diagnosis of FLUTD is based on the identification of signs of lower urinary tract inflammation.
Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body’s response to the injections needs to be regularly monitored by glucose curves over 12-24 hours. There are several glucometers that can be used at home for this purpose. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet. Hypoglycemia can result from too much insulin, not enough food, or excess exercise. Pet owners are trained to recognized hypoglycemia and treat or obtain emergency veterinary attention.
Diabetic ketoacidosis is a life-threatening condition that results from inadequate insulin or interference of insulin action on the body preventing glucose regulation. This causes a buildup of ketone bodies that, at a high enough level, will cause a metabolic derangement resulting in inability to retain water, weakness, vomiting and weight loss, among other signs. Treatment usually requires intensive hospitalized care including IV fluids, potassium supplementation, short acting insulin injections, and regular monitoring of glucose and electrolytes. In dogs already diagnosed with diabetes, ketoacidosis can often be prevented with regular glucose monitoring performed at home.